I love to use GUID's in my applications.  Today I was wondering just how unique a GUID is, and if I am safe to use them in my application.  Turns out that the use of GUID's does NOT guarantee a unique string every time, but the likelihood of a GUID not being unique is 1:340,282,000,000,000,000,000,000,000,000,000,000,000.  Yes, that is 340,282 with 33 zeros after it.

So, I would guess it is safe to use GUID's in the future.